I went directly from Nov 21 to May 22. "Favorite" navi destinations are all gone.I just completed the May update. Good news: It did NOT reset all the nav destinations, like the April update did.
However, being a software guy, I suspect that this update MAY reset your data if you did not already apply the April update. It's possible that the data structures changed with the April/May software, so the old saved destination structures might not be compatible with the current structures.
An alternative interpretation is that the clearing of the data by the April update was a bug, and was the reason that update was pulled from distribution. If that's what happened, then the May update won't clear your data even if you haven't previously applied the April update.
We'll have to wait until someone who didn't install the April update installs the May update to know which is correct.